modafinil will lower the level or impact of mavacamten by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
Be cautious at this dose, unless you’ve built up some tolerance to your good drug. Split dosing advisable each day. Not particularly advisable for any person but long-lasting end users.
The advised dosage of PROVIGIL for people with narcolepsy or OSA is two hundred mg taken orally as soon as daily as an individual dose in the morning.
Estrogen Derivatives: In patients working with put together oral contraceptive products (OCP), the maker endorses that patients use another technique of contraception, instead of or in addition to OCP, all through and right up until one particular month following finishing modafinil therapy.
Efficacy and safety of adjunctive modafinil treatment method on residual extreme daytime sleepiness among the nasal steady favourable airway pressure-addressed japanese clients with obstructive sleep apnea syndrome: a double-blind placebo-controlled examine.[J Clin Slumber Med. 2013]
If equally medicines are prescribed with each other, your doctor may change the dose or how often you utilize a person or both from the medicines.
eslicarbazepine acetate will raise the degree or result of modafinil by influencing hepatic enzyme CYP2C19 metabolism. Use Warning/Watch.
Geriatric Use: In aged people, modafinil and metabolite elimination could possibly be decreased, so consider using decreased doses and closely monitor people.
The advised dosage of PROVIGIL for clients with SWD is 200 mg taken orally the moment per day as one dose roughly one hour before the start in their perform shift.
Absorption: Modafinil is instantly absorbed immediately after oral administration. It can be insoluble in an aqueous Option and thus can't be administered intravenously. Most plasma concentration is achieved two-four several hours immediately after administration.
Other prescription drugs may well connect with modafinil, including prescription and in excess of-the-counter medicines, nutritional vitamins, and herbal goods. Explain to Every of your health treatment companies about all medicines you use now and any medicine You begin or halt utilizing.
Modafinil is accustomed to help Individuals who have narcolepsy, obstructive rest apnea/hypopnea syndrome (OSAHS), or shift work snooze problem (SWSD) to stay awake during the day. Modafinil won't heal these circumstances and may only operate so long as you continue to choose it.
efavirenz will lower the level or result of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
In 2008, Cephalon paid out $425m and pleaded responsible to some federal prison charge regarding its marketing of off-label click here utilizes for Provigil and two other medicine. ^